David Friedberg

“And I'm hopeful that tonight we can take an opportunity to hear about the evolution of the business and talk about some of those principles.”

“Most people in most enterprises that aren't owner operators don't want to fail. They want to keep their job. They want to move up the ladder by being repeatedly successful.”

“I just feel like Silicon Valley, a lot of companies replicate each other. You have to kind of there's this term that's being used a lot now over socialization.”

“They have more debt than they have assets and everything's getting more expensive and no one's moving up the economic ladder. There's no mobility anymore.”

“The success at Coke Industries is built on an algorithm, your principles, and you've been able to adapt that algorithm and as a result scale your business, generate cash, reinvest that cash, generate more cash, reinvest that cash and so on. And you've scaled 9,000 X. You've built a compounding advantage in your business.”

“And you've scaled 9,000 X. You've built a compounding advantage in your business. Right. As is the case with all successful capitalists, you build a compounding advantage.”

“The problem with compounding in any is it eventually eats all of the whatever is in the system or it makes it hard for others to compete in that system or participate effectively in that system. And that's the argument that's being made today against capitalism.”

“I actually think the moon is gonna be a giant, giant, giant economy. And I think it's like one of these economies.”

“if you get the cost of energy down to 1¢ a kilowatt hour, it absolutely expands every economy. Like, everything blows up. Like, imagine if you”

“AI seems to be solving that problem because they're now using AI to train the control of the magnetic fields in a way that's working.”

“Basically, you could use a a swimming pool sized amount of ocean water to make all the electricity needed for an entire year for the planet Earth.”

“Basically, you could use a a swimming pool sized amount of ocean water to make all the electricity needed for an entire year for the planet Earth. That's what this can do.”

“you could use a a swimming pool sized amount of ocean water to make all the electricity needed for an entire year for the planet Earth.”

“In 2016, another scientist published a series of papers showing that instead of putting a lot of those four proteins on the cell, you could put a small amount.”

“They're starting with targeting diseases, like a particular like like blindness or glaucoma in the eye or, you know, rheumatoid arthritis or some other heart issue, and they're applying these factors to the cells in that tissue only.”

“For every one year, we can extend average human lifespan. We're adding tens of trillions of dollars to GDP. Right? So this is also another big economic driver.”

“And if there's always a risk in going from animals to humans, but we've done it with human cells in in vitro, in a in a petri dish,”

“The estimate currently is that there's 600,000,000,000 to a trillion dollars in the whole. Okay?”

“That's now your private property. You own this stuff. That's yours. So now comes along the government or this new bill, the billionaire tax act in California.”

“Not a big chunk, but I've done my part. And 80,000,000,000 of that went to increase and it was supposed to go to increasing schools and, like, health care services.”

“Today, if you add up federal, state, local government employees, plus all the contractors for the government, plus all the people that live off of a retirement check or or a welfare support check, so all the people that are living off government checks, it's about nearly half The US population.”

“I think the moon could end up being kind of the next industrial frontier for humanity.”

“And the reason is if you can get to the moon, the moon has an extraordinary abundance of material that we can mine, process, and manufacture into goods.”

“It's about one sixth the gravity and the complete lack of an atmosphere, meaning that it's frictionless to move material off of the moon and very low energy to move it off of the moon.”

“So we could run continuous mining, continuous manufacturing processes on the moon at a fraction of the cost of what it would take to do it here on Earth.”

“And under the Biden years, I think is when Silicon Valley really felt like it came under attack.”

“And Silicon Valley kind of woke up to the fact that the government can play an outsized role in influencing, affecting how we might be able to operate and do business.”

“There's never been an empire that's been in the late stage that suddenly got a technology like AI.”

“I would argue that the robot is gonna be the biggest platform we've ever seen for economic mobility.”

“And I'm talking about somewhere between 250,000,000,000 and $1,000,000,000,000. California is bankrupt. That is a major Right. Fact that is completely ignored by”

“Practically no one is reaching their potential. Yeah. What AI does is it allows humans to reach their true potential Yeah. As a human.”

“What AI does is it allows humans to reach their true potential Yeah. As a human.”

“So there's more bacteria living in our gut than there are cells in our body. The human gut, as you guys know, has all these bacteria that can have a profound effect on your health,”

“99.9% of probiotics are absolute bullshit. Yeah. The placebo effect is a profound effect, and a lot of common allergy and skin based autoimmune stuff starts in the gut.”

“It's like the typical dosage is, like, one thirtieth or one fortieth of what's really gonna have an effect on your health.”

“And so it is an absolute game changer in terms of, like, having a permanent lasting effect in changing your gut. That's why we started the company. And so that was a couple years ago.”

“Like, companies are pumping out marketing all the time on this stuff, saying probiotics are so good. Probiotics are so good. It turns out 99.9% of probiotics are absolute bullshit.”

“So that's three servings of this is six grams. There's another one that's got eight. There's a and then we have a, you know, we still have a bar product.”

“GLP one just kinda, like, turns that part of your brain, that reward cycle. It's like, hey. You're you're good. Right. You don't need the reward cycle right now.”

“I don't think humans have, like, very well defined limits. Like, we have incredible potential. Every person has unbelievable potential.”

“I don't think, so I think, like, once you kind of start to realize that whatever you're being told you can't do isn't really a limitation, then you're free.”

“The rate at which you change things is more a predictor of success than doing the right thing. Yeah. And then I think the final thing is just curiosity.”

“We have $40,000,000,000,000 of debt and we're gonna have a $2,000,000,000,000 deficit this year. A trillion dollars of that is just interest on the existing debt. That number is getting bigger and bigger every year.”

“A bunch of programs are gonna run out of money, including social security, which is projected to run out of money sometime between, call it five and ten years from now.”

“Well, it's it's on the ballot now in California to pass a wealth tax, and it starts as a one time 5% tax for billionaires, but it gives the legislature in California the ability to lower the threshold and make it every year if they wanted to and change the percentage.”

“Well, it's it's on the ballot now in California to pass a wealth tax, and it starts as a one time 5% tax for billionaires, but it gives the legislature in California the ability to lower the threshold”

“You think we are gonna find ourselves in that conversation in 2028 and we're gonna have a national wealth tax where eventually just like we started with a 1% income tax, eventually everyone will pay a significant percentage of their net worth every year to support government services.”

“I've heard reports that the vast majority of US farms lost money. You're on the senate ag committee, which is why I'm asking this.”

“Do think we have a path to fixing agriculture in this country? And how do we get farmers back on track where they can earn a living without requiring checks from the government?”

“the Palisades fire a year ago destroyed 6,837 structures, including about 5,000 homes. And as of November 2025, only one home has been rebuilt.”

“I don't know if you followed this autonomous vehicle stuff in California, But, you know, for every million miles, autonomous vehicles reduce fatalities by, like, ninety five percent.”

“for every million miles, autonomous vehicles reduce fatalities by, like, ninety five percent. But if there's one autonomous vehicle that crashes once, everyone shuts that entire program down and says, wait a second.”

“But thinking through the second and third order effects of what would happen to kids if you kept them out of school for six months, what would happen to the economy if you shut down businesses.”

“There are some estimates that say that the pension shortfall in California for public employees that have retired is 600,000,000,000, maybe as high as a trillion dollars short of the legal obligations of payments that need to be made to those retirees”

“There are some estimates that say that the pension shortfall in California for public employees that have retired is 600,000,000,000, maybe as high as a trillion dollars short”

“That money has to come from somewhere. The United States is 40,000,000,000,000 in debt. We're burning 1,500,000,000,000, maybe 2,000,000,000,000 a year.”

“there's a proposal right from this guy, Dave Regan, who's the head of the SEIU, to do a one time 5% tax on anyone's net worth over $1,000,000,000.”

“By my estimate, more than half of Americans rely on a government check either directly or indirectly.”

“So you're either employed by the federal, state, or local government or its agencies or one of its contractors, or you're receiving one of the retirement checks from a government agency.”

“And so it's become very difficult because a majority of the population is receiving benefit or living from some sort of government flow of capital,”

“I saw the statistic yesterday that I think 1,100 bills get signed into law a year out of the state assembly because it's a uniparty state.”

“someone told me a statistic that 4,000 family offices have been opened in the last ten years or so in Singapore.”

“4,000 family offices have been opened in the last ten years or so in Singapore. Underestimate, probably. Yes.”

“the city of San Francisco has a managed alcohol program where they will give out beer and vodka to homeless alcoholics that they can come and get any time of the day, twenty four hours in hotel lobbies where they walk in, they are given either they can choose a vodka or a beer.”

“there are reports that they've given out 17 shots of vodka in a single night to a homeless person. And this is like a 5 to $10,000,000 a year program”

“there are reports that they've given out 17 shots of vodka in a single night to a homeless person.”

“And as a result, there's no market check. So in the case of education, the colleges can charge more every year, and the student is free to just get more loans.”

“My salary will go from $1.30 to 200 if I become a manager and hire four people. Fast forward thirty years, 10% of staff as administrators to 60% of staff as administrators.”

“a statistic. In twenty fifteen, ten years ago, papers published by Chinese research labs and major scientific journals were about half of The United States. Yeah. Now 50% more than The United States.”

“In twenty fifteen, ten years ago, papers published by Chinese research labs and major scientific journals were about half of The United States. Yeah. Now 50% more than The United States.”

“Just try to think about each one of those being one, maybe one and a half gigawatts. Suddenly, that's 60% of The US power production capacity being built right now in just nuclear by China.”

“Just try to think about each one of those being one, maybe one and a half gigawatts. Suddenly, that's 60% of The US power production capacity being built right now”

“Suddenly, that's 60% of The US power production capacity being built right now in just nuclear by China.”

“at the time, it improved up to $60,000 of income a year Right. Then it flatlined beyond And then the the the key measure of happiness was income change year over year.”

“the key measure of happiness was income change year over year. The more your income changes from one year to the next, the happier you are.”

“four you know, four forty million Americans graduated in last ten years from student from college with student loan. Average student loan debt $440,000.”

“And most of those kids came from a middle class family where they had positive assets. The parents own the house. Now the kids that voted for Mamdani cannot buy a home.”

“Let me just kind of describe another way. The macroscopic system could be my entire body. Could I walk through a wall?”

“The the probability of all of my atoms being in the perfect moment, perfect position, you know, to to be able to kind of cross through the wall is so low, it would never happen in this or many other universes.”

“I got really fascinated by superconductors when I was maybe 12 years old. I I went and bought a superconducting disc, yttrium barium copper oxide”

“That's From the back of Popular Science. And then I went to UCLA, I got a a jug of liquid nitrogen. And then I floated a magnet above the disc”

“Because of the Meissner effect. And I had it at the science fair, and I and I did very well with the science fair that year because I showed this really cool.”

“I've always, thought and there's obviously been companies started around the idea of creating an infinite battery where you could store technically forever electricity because the electrons are just moving around.”

“I mean, it's very interesting. And I think just this broad question or observation that sometimes inquisitive minds leads to research that leads to some set of discoveries that are completely not apparent until forty years later, the effect or the impact it may have had”

“And I think just this broad question or observation that sometimes inquisitive minds leads to research that leads to some set of discoveries that are completely not apparent until forty years later, the effect or the impact it may have had Yeah. On building an industrial field.”

“I left all my stock options on the table, all my RSUs I'd been given. It was worth a couple million dollars, and I was 25 years old back in 2005.”

“And Danny's like, I'll introduce you to all the VCs in the Valley. I had met two of them from Google's board meetings, Mike Moritz and John Doors.”

“this guy always said, you can never have too much data, and you can never have too little data. Any amount of data gives you more than none and gives you predictive capability.”

“Any amount of data gives you more than none and gives you predictive capability. And the more data you get, the better your predictive capability gets.”

“I raised, like, $2,200,000 from friends and, like, networking to other people that Danny had introduced me and that my friends introduced me to.”

“I launched the thing in January of o seven, and I'm going to conferences and trade shows trying to sell the product, and everyone's saying no.”

“And then we had the idea of charging for certain add ons, certain models. Like, it would recommend what seed to use and recommend what fertilizer to use”

“And I think 80% of harvesters and tractors in The US have an iPad that runs that software, and it's connected to the farm equipment.”

“No. I think if you ask people that work in and around the industry, a lot of people call the acquisition of Climate by Monsanto because they paid $1,100,000,000.”

“No matter what startup tells you, whatever they're gonna tell you, it's all 10 x more expensive. Some of them are coming down.”

“And what they did is they created a chemo enzymatic system, meaning chemical and then enzymes, that could synthesize starch from atmospheric carbon.”

“Agriculture, I tell people, is difficult because you have a seasonal cycle, you only get to sell once a year. You don't know until the end of the year how it's going.”

“I was really convinced that building software for agriculture could work and should be the future, and we should do that.”

“How do we retain our agents from last year? Just all the typical stuff that goes on with scaling a business.”

“I think something that I say to many students when I so I do one on one ALPS tutoring, and I work on exam strategies, overcoming anxiety, creating study plans, and so much more.”

“When I work with students, something that I started saying is move on from the past to focus on the present to create the future.”

“The reason I started thinking this way and saying this is because you have to move on from that past.”

“Because if you don't move on from all of that, you're not gonna focus on what's in front of you.”

“I may not know everything, but I know enough to pass. I will pass. And I would tell myself that over and over and over again.”

“You accepted it, but you're not growing from it. Once you actually learn from that, then you have that growth and you have a progression.”

“It was like a twenty four day intensive wrestling camp in Minnesota. I forgot how many days specifically, but it was a Jay Robinson wrestling camp at the University of Minnesota.”

“I don't think that that would be valid to utilize any longer, but I would go by I do a pro wrestling podcast, and sometimes I use this this little nickname.”

“I have a heart of a lion. I will not stop. I have a lot of grit. I know that for a fact.”

“I saw a poem that said, it was the devil whispers, you can't withstand the storm. The warrior replied, I am the storm. Once I saw that, I started to associate myself as a warrior.”

“The warrior replied, I am the storm. Once I saw that, I started to associate myself as a warrior. And then I started saying, I am a final frontier warrior.”

“I view this company as my I I have ownership in this. I don't actually have ownership in this, but my mentality is I do have ownership in this.”

“I started saying is move on from the past to focus on the present to create the future.”

“move on from the past to focus on the present to create the future. So the reason I started thinking this way and saying this is because you have to move on from that past.”

“So that's where I started saying, I have studied a lot. I may not know everything, but I know enough to pass. I will pass.”

“I may not know everything, but I know enough to pass. I will pass. And I would tell myself that over and over and over again.”

“It was, like, a twenty four day intensive wrestling camp in Minnesota. I forgot how many days specifically, but it was a Jay Robinson wrestling camp at the University of Minnesota.”

“Like you could make hundreds of millions of dollars if it worked out and it became a massive show, but you're basically capped at Netflix.”

“Everyone thinks that technology always has a catch. There's always something bad emerging. Robots are gonna kill us all. AI is gonna wipe out human civilization. Nuclear power is gonna melt down and destroy neighborhoods.”

“You watch all the shows on Netflix, you watch all the movies, Aaron Brockovich, like the ones that work, the ones that seem to resonate, which means that's what people truly kind of want, are the ones that talk about things gone wrong,”

“your show is quite different and you talk about what if things go right, why do you think that is resonating and are we changing or is it Are you kind of capturing a small audience and the bigger one still sort of techno pessimistic?”

“There's a YouTube video called the Disney History Institute, the channel, and it shows, like, what Tomorrowland was like when when Disney opened in 1955.”

“And it was all about like, we're building this better world with all of these crazy technologies, rockets to the moon, plastics so we could all have cheap furniture.”

“And it was all about like, we're building this better world with all of these crazy technologies,”

“To a point that at a certain distance from us, the objects in whatever direction we look are moving away from us at nearly the speed of light or even faster.”

“As you're launching in The US, do you have a sense Keller, are you gonna beat the unit cost to deliver with delivery drivers today and by how much?”

“So now we can take that seed and farmers can use it to plant. So eventually, handful of seed replaces warehouses of potato chopped up potato that are being put in the ground.”

“I cannot control a company, I cannot direct a company, I cannot lead a company from the board.”

“it feels like when you're on the board, every day you're waiting for shit to happen. But if you're the CEO, every day you get to wake up and make shit happen.”

“Yeah. And that's what it feels like to me, you know, being able to step back into an operating role as CEO again”

“So while a potato might make 12,000 seed from the flowers that grow out of that potato, every single one of those seed is genetically different.”

“I generally think that ag products should be built and priced on a value creation system. So, you know, this is the Monsanto pricing model.”

“And that $5,000 of revenue is requiring an investment of 1 to $2,000 an acre. So 20 to 40% of revenue to deal with all of the planting and fumigation and storage”

“You could probably see that you could save at least 15 or create at least $1,500 an acre of operating profit improvement for that potato grower.”

“I think that the ag market is going through a lot of fantastic innovation cycles right now. Everyone views the ag tech market negatively because the returns for the ag tech investor class isn't there.”

“But that doesn't mean that ag tech isn't innovating, and that we aren't improving productivity and bringing value to farmers and improving the quality of our food systems.”

“I mean, always tell people like at Climate Corp, if you miss your sales window by a couple of days, you got to wait another year.”

“I'll give him a shout out because he still works at Climate Corp to this day I hired him after so he sold me a CD ROM of weather data.”

“It was 17 megabytes of data. That's like as much data as you get when you take a photo on your iPhone now or two photos on your iPhone pretty much.”

“And in every experiment we ran, the results were incredible. The yield goes through the roof. Everything we expected would happen, happened. The genetic diversity creates hybrid vigor, creates faster growing healthier plants, bigger plants.”

“So the global potato industry is about 100,000,000,000 a year. And, I'm not sure if you guys have ever visited a potato farm, but potato farm potatoes are vegetatively propagated.”

“With boosted with our system, not only can we breed potato, but we can then make uniform seed. So every seed that comes out of that potato is the same.”

“So eventually a handful of seed replaces warehouses of potato, chopped up potato that are being put in the ground.”

“Around the world, potatoes are a very significant staple crop, third largest source of calories for humans on earth.”

“Okay? And that $5,000 of revenue is requiring an investment of 1 to $2,000 an acre.”

“You know, you can probably see that you could save at least 15 or create at least $1,500 an acre of operating profit improvement for that potato grower.”

“And in the popular poll ons, it's called GMO. That system allowed us to introduce proteins into plants that aren't native to that plant.”

“But that doesn't mean that ag tech isn't innovating and that we aren't improving productivity and bringing value to farmers and improving the quality of our food systems.”

“You know, you get to keep your sales cycle going all the time. In ag tech, you have seasonal cycles that you're kind of stuck to.”

“The sales guy was a guy named Jeff Hamlin. I'll give him a shout out because he still works at Climate Corp to this day.”

“So Laura asked AI to write a Python script for her, to download all the resumes from Greenhouse, scan them, score them, and give her results. She did this all in a couple of hours.”

“Laura asked AI to write a Python script for her, to download all the resumes from Greenhouse, scan them, score them, and give her results. She did this all in a couple of hours.”

“I actually think the addressable economic opportunity for startups has actually grown. So startups that otherwise might not have been able with 50 or 100 people to go after a multi billion dollar seed market, which is kind of the market that we're in, can now do so because of the leverage they get with AI.”

“And then how are you gonna refine the ore? Every one of those steps of that deeply complicated, highly technical project can now be run-in Silico.”

“I can design a project plan to get me to the moon in five years for less than a billion dollars.”

“I can design a project plan to get to Mars and ship an entire city to Mars in less than fifteen years for less than $50,000,000,000.”

“So for example, when anyone asks for head count, ask them, Why can't AI do the job? Right.”

“Ask those questions. And so maybe every job description that needs to get approved by leadership, and the first paragraph is, why aren't you using AI?”

“They're farmed vegetatively, so you actually chop up leftover potatoes and put them back in the ground in order to grow potatoes, like Matt Damon does in The Martian.”

“And with our system, you can put less than 10 grams of little tiny seed to replace that two and a half tons of potato.”

“So theoretically, we could make any element we want if energy costs were low enough.”

“So, you know, we have if robots are making all of our stuff, we could get robots to make housing for us, make roads for us.”

“Under your tenure as CEO, the stock has gone up by four and a half x to a $2,000,000,000,000 market cap today. You've grown revenue from 20,000,000,000 a quarter to nearly 100,000,000,000 a quarter.”

“the core search business, which the ad revenue in search is about a $200,000,000,000 run rate out of $360,000,000,000 of your total revenue, most of your profits.”

“the ad revenue in search is about a $200,000,000,000 run rate out of $360,000,000,000 of your total revenue, most of your profits.”

“Urs and his team were building these super secret shipping container data centers. They had these like data center in a box that you could ship anywhere.”

“As long as you had access to water and power, it could connect to the internet and you could scale data center capacity all over the world. That was twenty years ago.”

“Elon this week is saying, hey, need a terawatt of compute. Terawatt is roughly the power production or the electricity production capacity of the entire United States.”

“Terawatt is roughly the power production or the electricity production capacity of the entire United States. US is going from one to two between now and 2040.”

“I always tell people I think they underappreciate the role that Bell Labs played in driving innovation and ultimately human prosperity in the early twentieth century.”

“The US is forecasted to increase its electricity production capacity from one to two terawatts by twenty forty, fifteen years from now.”

“So in the next fifteen years, China is adding five Americas. Yes. In electricity production capacity.”

“We just got back from DC. There is this hill and valley forum this week. Every single speech, every single talk, every conversation in the hallways was all about the energy demand coming from AI.”

“There's gonna be a breakthrough in the next year or two that's gonna unleash this additional demand curve. We're gonna have a 100,000,000 robots in The United States. They're all electrified.”

“You gave me a statistic, which I hadn't heard before, which is we only graduate 200 people in degrees in mining today. Why did we stop mining?”

“So every cell in our body gets its energy, which is what it uses to function from the mitochondria.”

“And, this paper, Nick, if you could just pull up that image of mitochondria being transferred, these folks identified and demonstrated that mitochondria can actually transfer from one cell to another.”

“So if you've got a cell that's got damaged or dysfunctional mitochondria, they've identified three mechanisms by which mitochondria can move into a cell that needs more mitochondria that are working and are more functional.”

“The second paper was done, last month out of Columbia University, and this was the first mapping of the mitochondria in the human brain.”

“So what these guys did, which was really incredible, is they took stem cells. So stem cells that they got out of human blood and they took those stem cells and they figured out a way to treat the stem cells so that those stem cells would start to make an excess amount of mitochondria than they normally would make.”

“In fact, they were able to get those stem cells to make eight fifty four times the number of mitochondria that those cells would normally make.”

“And those mitochondria were on average 5.7 times more efficient at making energy, ATP. So they created highly energetic mitochondria and they made a lot of them.”

“So this mechanism that they developed where they could take stem cells, make copies of the stem cells, make lots of mitochondria, and then they isolate that mitochondria and use it as a therapeutic tool.”

“So, this is a group that does bone and tissue repair studies, but they applied the mitochondria directly into the area where there was damage to the bone, and the bone grew back, and it actually improved the healing in an incredible way.”

“So this opens up the door to this whole new therapeutic modality, a new type of therapy called mitotherapy or mitochondrial therapy that based on the series of papers that we're seeing coming out recently, I believe could end up becoming a really incredible new therapy that may ultimately lead to the treatment for many diseases”

“But you could see this being applied, for example, to cerebrospinal fluid where you could basically increase the mitochondrial, the energetic mitochondrial production that finds its way into maybe neuronal cells, into neurons in your brain and improves, your brain function, or you could put it into damaged hearts after heart attacks and improve heart function.”

“So it unlocks a significant yield gain and it creates new opportunities for creating seed products in markets where it doesn't exist.”

“Potato farmers today use about 10% of their harvest to replant leftover potato vegetative biomass back in the ground. That's how they're doing planting.”

“It takes a lot of fuel, lot of labor, and it's pretty resource intensive. And then there's obviously a pretty significant fumigation effort that goes on.”

“They were able to suck up all the text on the internet and use that text to make a prediction on what the answer should be when someone asks a question word by word.”

“I can now build models that some people are calling genome language models or, you know, whatever you wanna call them that can be predictive of a phenotype.”

“And that's because I think that the benefit, the economic benefit to the smallholder farmer in emerging markets is so profound.”

“Someone quoted me this, so I'm simply stating their quote. I don't have direct data that I'm representing here, but their estimate is that the the labor cost in strawberry farming in The United States has grown from 700,000,000 a year to 2,000,000,000 a year in four years. So that's a huge tripling of labor cost.”

“Someone quoted me this, so I'm simply stating their quote. I don't have direct data that I'm representing here, but their estimate is that the the labor cost in strawberry farming in The United States has grown from 700,000,000 a year to 2,000,000,000 a year in four years.”

“And the Chevron doctrine basically allowed agencies vested agencies authority to make regulatory, rules that can then be imposed legally, statutorily.”

“We've developed a new system of of breeding that we call boosted breeding that really changes how we do breeding, the pace of gains, and also allows for true seed propagation in plants where we're typically doing vegetative propagation where there isn't a seed business today.”

“So it unlocks a significant yield gain and it creates new opportunities for creating seed products in markets where it doesn't exist.”

“Potato farmers today use about 10% of their harvest to replant leftover potato vegetative biomass back in the ground. That's how they're doing planting.”

“And so we could reduce that cost down, we think by over 75% if we can move to a true seed model.”

“Turns out plants are very good at accessing the gene they need when they need it.”

“And that's because I think that the benefit, the economic benefit to the smallholder farmer in emerging markets is so profound.”

“I'll give you an example in Strawberry. Someone quoted me this, so I'm simply stating their quote.”

“Someone quoted me this, so I'm simply stating their quote. I don't have direct data that I'm representing here, but their estimate is that the the labor cost in strawberry farming in The United States has grown from 700,000,000 a year to 2,000,000,000 a year in four years. So that's a huge tripling of labor cost.”

“Someone quoted me this, so I'm simply stating their quote. I don't have direct data that I'm representing here, but their estimate is that the the labor cost in strawberry farming in The United States has grown from 700,000,000 a year to 2,000,000,000 a year in four years.”

“I do think that there's going be some big opportunities for the next transformation in agriculture in multiplex precision gene editing and in, metagenomics in the soil microbiome, even in breakthroughs in biologics or other platforms that can discover the next, set or the next range of biologics.”

“I think the world will be surprised by how much we see acceleration and advancement in productivity in ag and food systems in the next ten years.”

“I do think that there's gonna be some big opportunities for the next transformation in agriculture in multiplex precision gene editing, and in metagenomics in the soil microbiome, even in breakthroughs in biologics or other platforms that can discover the next set, or the next range of biologics.”

“So there's a massive transformation happening in plant breeding. What used to be, you know, a seven to thirteen year cycle, you can actually do a 100 times better than that by doing precision gene editing in a year, and in biologics, there's so many products that seem to have extraordinary potential at replacing traditional inputs, biopesticides, bio fertilizers,”

“So what's happened in biologicals is historically input companies would try and inoculate microbes or get them to grow that they were grabbing from the environment.”

“Now DNA sequencing costs have gotten so cheap, right? Twenty years ago it cost $100,000,000 to sequence the human genome. Today it costs 100, and you can do it in a few hours.”

“At the end of twenty twenty one, there was a paper published by a team in China where they demonstrated a chemo enzymatic system for synthesizing starch. Starch is amylose and amylopectin, two molecules.”

“this team identified seven enzymes from plants that basically catalyze the transformation of sugars over to starch into amylose and amylopectin.”

“Now the efficiency of this system was nine times more efficient than corn, is what they demonstrated.”

“I think the world will be surprised by how much we see acceleration and advancement in productivity in ag and food systems in the next ten years.”

“having seen how turning certain genes on or off in a plant can extraordinarily expand the productivity of that plant and increase farmers' yields by 50% per acre, by just turning a gene off.”

“It really is astounding what we can do today that we literally couldn't do ten years ago.”

“In the seven years we ran Climate Corp, by the way, we did a study that our average data use per year increased by 40x every year for seven years.”

“We are proposing the federal administration is proposing a $7,000,000,000,000 budget next year. We have $33,000,000,000,000 of national debt.”

“And when that happens, you know, 2% increase in interest on $15,000,000,000,000 that's another $300,000,000,000 of interest payments a year.”

“And this year, we're already paying a trillion dollars just in interest on the debt that the federal government owes to its bondholders, to the people that own treasuries.”

“Your change in income is your predictor of happiness. So if we start with that premise of like human behavior, the government now has an incredible the federal government in The United States has an incredible role in supporting a lot of people through active programs that pump money into businesses.”

“I tried to pull together all this data a couple months ago, but something north of like 30 or 40% of The US working force is touched by the government as a customer of their business, the primary customer of their business or as the employer of those individuals.”

“That's how people get elected in a democracy. They go to the voters, they say, here's what I'm going to give you.”

“In 1955, Disneyland opened, I've told this story before with this ride called Tomorrowland. This area called Tomorrowland. I mean, you've been there. And every ride there was about the future opportunity with technology.”

“In the nineteen seventies, they started to turn over all the rides in Tomorrowland at Disneyland and every ride got remade as a fear of technology ride.”

“And when he died, they put a stop on gene therapy treatments for I think seven years. They weren't allowed to do any more gene therapy treatments.”

“They weren't allowed to do any more gene therapy treatments. And since then we now have literally dozens of gene therapy treatments that can cure dozens of human diseases saving millions of lives.”

“When the reality is equal opportunity, everyone has access to participate is what really drives success and drives equality.”

“Of that 30,000,000,000 acres, 15,000,000,000 are where we grow stuff. 3,000,000,000 is crops, 12,000,000,000 is animals.”

“today on planet Earth, there's about 800,000,000 people worldwide that still live on less than 1,200 calories a day. They are technically deemed malnourished by the UN, by the FAO.”

“And so by the year 2050, the UN estimates we'll need to increase global food production by north of 50%.”

“by the year 2050, the UN estimates we'll need to increase global food production by north of 50%. So the way we're doing that is we're eating into the Amazon.”

“what would happen if we could get the sex cells to have all the DNA of the mother and all the DNA of the father, the complete genome?”

“The idea was we could turn off the process that causes the fusion, the reduction of the DNA, and have it have all the DNA. And so we did this. It started to work.”

“And so we started to do it, and the results were incredible. We saw 50 to a 100% plus gain in yield in the offspring.”

“we've still been farming Russet Burbank in The US for a hundred plus years. That's a hundred year old variety.”

“We got it to work. We got the results that we predicted, and we were blown away. It's, like, consistently positive results, consistent performance.”

“The company, Ohalo, is named after a site discovered next to the Sea Of Galilee called Ohalo 2. It's an archaeological site.”

“Right now, we are on the wrong side of the malnourishment curve. Malnourishment is increasing on Earth.”

“Malnourishment is increasing on Earth. We spent thirty years getting it to decline. It's now going back up. And climate change is making things more difficult in Brazil.”

“But you don't have to make the trade offs like you do in plant breeding today, where you give up other good traits in order to try and stack those two traits together.”

“We were able to change the genetic circuits that control for meiosis and mitosis and make this happen. We did it across multiple plant species.”

“in every experiment we ran, the results were incredible. The yield goes through the roof. Everything we expected would happen happened. The genetic diversity creates hybrid vigor,”

“when you're on the board, every day you're waiting for shit to happen. But if you're the CEO, every day you get to wake up and make shit happen.”

“So the global potato industry is about a $100,000,000,000 a year. And, I'm not sure if you guys have ever visited a potato farm, but potato farm potatoes”

“So the global potato industry is about a $100,000,000,000 a year. And, I'm not sure if you guys have ever visited a potato farm, but potato farm potatoes are vegetatively propagated.”

“the global potato industry is about a $100,000,000,000 a year. And, I'm not sure if you guys have ever visited a potato farm, but potato farm potatoes are vegetatively propagated.”

“With boosted, with our system, not only can we breed potato, but we can then make uniform seed. So every seed that comes out of that potato is the same.”

“eventually, a handful of seed replaces warehouses of potato chopped up potato that are being put in the ground. So you can move to an, you know, a low cost, more energy, more environmentally friendly,”

“potatoes are a very significant staple crop, third largest source of calories for humans on Earth. 95% or 90% of the potato grown in India, for example, are used in table potatoes.”

“I generally think that ag products should be built and priced on a value creation system. So, you know, this is the Monsanto pricing model.”

“That potato farmer today is spending somewhere between one top line, that potato farmer is making about $5,000 an acre in The US. K?”

“that doesn't mean that ag tech isn't innovating and that we aren't improving productivity and bringing value to farmers and improving the quality of our food systems.”

“In ag tech, you have seasonal cycles that you're kind of stuck to, so you don't get the results for a while.”

“And farmers don't wanna pay for data. They wanna pay for results. So that's a that's kind of a very hard thing to do without the the integration of data.”

“when I started Climate Corp 2006, the first thing I did when I got a seed check to start the company is I went out and bought weather data, and I bought it from a company called RMS that sold weather data. The sales guy was a guy named Jeff Hamlin.”

“In the past ten years, if you bought the top 10 stocks on the NASDAQ, you would have made 10 x. Okay. It's a crazy statistic.”

“And those big thinking, those big ideas, those big audacious concepts, as a framing for the team, really, I think personified what I consider to be true leadership in an organization of people,”

“Well, there's I don't know about, using the term thinker, but I think that the, the big concepts are scary because there's so many things that have to go right to get them to work.”

“And, you know, complexity breeds fear because it breeds a higher chance of failure. You know, you have to get each of these things right for something to work.”

“And you could probably make 50,000,000 in return. That's a nice little 10 bagger. Great. Let's do that. And then let's plow a trillion dollars into that concept.”

“And we had to get multiple things right in a row over time to see if this thing even worked. And fortunately it works, but it took us four and a half years.”

“But because we remained committed to the bigger idea, this bigger experiment we had, this big project, We had a shot at it, and we got there, and this thing worked.”

“On the rest of the portfolio where things were up rounds and things were going well and they put more money in, they made a lot of money.”

“And in The Us while the average is one seventy five, there are farmers who regularly get over 300 bushels.”

“And then seeing this outcome that we had theorized, all of that has now been proven with this business.”

“In the last two years since COVID, we've unfortunately seen a reversal in global malnutrition statistics. You know, we were at 600,000,000 people, living on less than 1,500 calories a day just before COVID.”

“At that time, probably the largest we were known to be the largest users of Amazon's Elastic Compute Cloud because we were ingesting so much data to build these models that related all the variables of farming and the weather to predict outcome.”

“In fact, we did federal Freedom of Information Act requests for the federal government in The U. S. To get hard drives and hard drives of data.”

“So I was like, well, in order to pull that off, we really have to do good for our last round's investors and kinda had a hefty negotiation to get the deal done.”

“Farmers want to pay for value. I want to pay for ROI. I want to spend $8 and get $60 back.”

“What used to be, you know, a seven to thirteen year cycle, you can actually do a 100 times better than that by doing precision gene editing in a year.”

“Twenty years ago it cost a $100,000,000 to sequence the human genome. Today it costs a 100, and you can do it in a few hours.”

“And so the hit rate for biologicals one point zero in the way that they were being sold in the traditional input cycle inputs model, not very good.”

“Now the efficiency of this system was nine times more efficient than corn, is what they demonstrated.”

“And since then, hundreds of other gene editing tools have come to market, many of which are open sourced or royalty free”

“In the seven years we ran Climate Corp, by the way, we did a study that our average data use per year increased by 40x every year for seven years.”

“I'm not a huge believer or a huge fan of businesses that depend on kind of greenwashing and charging a premium to people to make themselves feel better about the decisions that they're making.”

“They're coming up the economic ladder and they're gonna eat more meat and they're gonna eat what tastes good and they're gonna eat whatever they can afford.”

“Most people don't realize when you haven't built a business from the ground up, but 99% of your assumptions are wrong going into it.”

“They don't have this ability to drive narrative to tell this compelling story. They won't attract the right team. They won't be able to attract capital, and they won't be able to get customers.”

“There are many biotech companies. There are a number of kind of consumer hardware, there's also a number of kind of enterprise hardware, lab automation.”

“When interest rates jump up to 4%, well, now I can invest my money and I can make 20% back on my money in four and a half years.”

“I think two thirds of the companies that went public since COVID are trading at less than the cash they raised to date as public companies now.”

“There's a product that there's literally no GMO version of an input, of oats. There's no GMO oats. So an oatmeal company puts out a box and they say, Here's our oatmeal.”

“95% of the world's population is going to live in Africa and South Asia by the end of this century.”

“And you put them together in a bunch of tanks, and then they can take carbon out of the atmosphere and they can actually make starch.”

“I think the top 700 microbrews in The US now outsell Budweiser and Miller. Okay. And that's an incredible statistic. So, I don't know what Do you drink beer?”

“They love who he is. And he's like, hey, guys. I got this chocolate bar. His chocolate bar, Feastables, outsells Hershey's and the store's at a tip.”

“So I think what we'll see is this really interesting integration of content with brands. And as a result, the content driven strategy starts to lead the advertising and marketing driven strategy.”

“I think it's about, you know, we we can aggregate more money through a central source, some federal grants or or what have you.”

“The problem with decentralized networks is often you see adverse selection. You see this in, like, the insurance industry.”

“You see this in, like, the insurance industry. The term is often used to adverse selection where, it's the best storyteller that wins, not necessarily the best candidate.”

“And they've been going out and just grabbing some of the best academic and research teams out there that are like, they brought a ton of people out from UCSF.”

“I think it's a really interesting model. I'm really curious to see what comes out of Altos Labs, given that the number of teams that they've gone out and like vacuumed up from academia, the probability of that portfolio of teams having a breakthrough or a set of breakthroughs that has commercial success is very high.”

“The challenge arises that that science then either gets licensed out in a way that UC doesn't benefit enough from the discovery that was made, where they own the IP, or they're just not open sourcing it. Those are the two problems. And what happens often is something in the middle.”

“And I said and I have my board, and I said, here's all the things you're gonna be able to do with superconductors in the future, and it's gonna totally change the world.”

“And the absolute on narrative is a guy like Elon Musk, who could show up, tell you he's gonna do something and then not do it Mhmm.”

“Yep. Now digital technologies have driven the cost down of DNA sequencing faster than Moore's Law in the past twenty years.”

“So the number of papers on the gut biome has kind of grown geometrically last couple years.”

“And increasingly, there's evidence as published a few weeks ago in two different papers, including one out of led by a team out of Harvard, that it may be dysfunctions not in the genome and the DNA, but actually dysfunctions in the epigenome, which is the molecules that sit on the DNA.”

“So we've increased energy production by about 20 fold in the last hundred years on earth. I think in the next hundred years, we can and should increase energy production by over a 100 fold.”

“Great. But they're not going to kind of replace everything. Fission has this regulatory. So we have to have a portfolio of stuff.”

“So we have to have a portfolio of stuff. Fusion, from a first principles perspective, as you know, works because we see it working in the sky. So we know that this physics is real.”

“So a couple of years ago, three years ago, was about seven venture funded fusion companies. As of the end of last year, Q3 of last year, count was 47.”

“And so the global economy collapsing or being very shaky right now and the US dollar rallying is not good for us.”

“We're spending $800,000,000,000 a year on debt service right now. That could skyrocket to $1,500,000,000,000 which is over a third of the federal budget each year going into next year.”

“So the first thing we saw inflate was sort of hard commodities and soft commodities, things like energy and agricultural products and metals and so on.”

“the UN World Food Programme has declared that we're marching towards 300,000,000 incremental people that are facing undernourishment and starvation in 2023 because of the food shortages that are arising from the increment in fertilizer prices. And no one's really paying attention to this or thinking about it.”

“And no one's really paying attention to this or thinking about it. But when it starts to hit, The US is already spending $5,000,000,000 a year supporting the World Food Program”

“And they were all delisted around the world. Over $600,000,000,000 of value was wiped out. Those shares were largely owned by pension funds”

“And so part of our economic sanctioning of removing Russian stocks from European and US listed stock exchanges caused a $600,000,000,000 wipeout in value”

“Because of the fast feedback cycles that we talked about earlier, and that a point of view, kind of the mob coalesces around the point of view, you end up electing the person who represents the mob, which means that ultimately over time in a democracy, in the social media age, is you don't end up electing leadership.”

“leadership, as Sax points out, needs to and has to be willing and able to lead, which means being contrarian and being inspiring.”

“What I think is the biggest driver of shifting politics today is the difference between equality of opportunity and equality of outcome.”

“Yeah. So believe it or not, there are what are called fecal microbiota transplants, FMTs.”

“the simple model of success in life is you do something, you succeed, you consider yourself successful, But then when you get knocked down, it's very hard to think about yourself still being successful or having the potential to be successful if your model, your learned model is success.”

“Yeah, so those are my three traits that I think are the greatest predictors of entrepreneurial success.”

“And you cannot tell me of a successful story of entrepreneurism where the entrepreneur did not exhibit an extraordinarily high index on at least one of those three traits.”

“So grit, if you never give up, you definitionally will not die. You could get paid zero salary, have no office and keep going. And that business eventually will find a path.”

“The individuals who possess a strong storytelling trait, an ability to paint a picture that elicits emotional context in the listener in a way that drives them to act is a person that can infinitely fundraise, that can attract and recruit the best employees, that can sell customers on a product that doesn't even exist yet.”

“To make a gram of animal protein, or let's say like 100 calories of animal protein, it takes 3,000 calories of energy into a system to make that animal protein.”

“our objective shouldn't be about in sustainability, shouldn't be about, hey, can we get people to consume less? It should be, can we get people to consume more?”

“Yeah, so people spend $2,000,000,000,000 a year on canned and bottled beverages from wine and beer, which is a trillion to coffee, tea, juice and soda, which is another trillion.”

“If you already have a 100,000,000 people following you like MrBeast does, he just goes on his video and he says, buy my chocolate bar. And he sells 50,000,000 chocolate bars.”

“if you look at the amount of electricity that humans consume on planet Earth today, it would take about a 10 meter by 10 meter by 10 meter cube of ocean water to make all the electricity that we consume today if we could put that into a plasma fusion system”

“I'm a big believer that sustainability in the twenty first century does not arise from convincing consumers to consume less. I think sustainability arises from building technology based solutions that let consumers consume more”

“Wesley and I kind of started working together after that because the first thing Larry and Sergei said to me was that's evil. Third party cookies are evil.”

“Within a year, I think we had shown through Hal Varian, who was our chief economist, we had demonstrated that Google Analytics increased AdWords revenue by $500,000,000 because so many advertisers were using it to improve their websites and make the conversions better that they were spending more on AdWords.”

“99% of beverages are water or maybe water plus sugar, or maybe water plus alcohol.”

“And so we're starting preorders today for for $99. You can reserve a fully refundable $99 reservation fee. And the first 10,000 orders are are $4.99 for the device and $7.99 after the first 10,000.”

“only 3% of beverage brands that launch and get retail space actually make it to 10,000,000 in sales.”

“I think sustainability arises from building technology based solutions that let consumers consume more and dropping the price and dropping the environmental impact.”

“It's about half a billion tons of CO2 that are put into the atmosphere every year to make bottled cans and beverages. Is about bottled and canned beverages.”

“It is about 400,000,000,000,000 liters of water that are used in the whole production cycle of bottled beverages. And consumers are spending $2,300,000,000,000 a year on this archaic, insane system of centralized manufacturing”

“120,000,000 acres of farmland that could be reduced and returned back to the natural ecosystems that we would stop using to grow all this stuff.”

“120,000,000 acres of farmland that could be reduced and returned back to the natural ecosystems that we would stop using to grow all this stuff. So that's our long term incentive, right?”

“Companies generally have a lower operating expense per customer so they can make less profit per customer and build a great business.”

“And so they can make the investment to take a more aggressive approach, make less money per customer per year and gain scale very quickly.”

“And if they do that, they lose the leverage of their over their existing customer base, which is to cross sell digital services in.”

“And if they try and do that, then they step in and they try and run a tech company and the whole thing gets ruined and falls apart as we've seen in M and A over and over again in many different So it is this kind of classic innovator dilemma moment that we're seeing in financial services”

“And if they try and do that, then they step in and they try and run a tech company and the whole thing gets ruined and falls apart as we've seen in M and A over and over again in many different”

“So it is this kind of classic innovator dilemma moment that we're seeing in financial services as the fintech companies kind of storm the field.”

“I feel like the the Robinhood fine the FINRA fine of $70,000,000, was a good red herring for what's gonna happen in this industry which is that the big financial services firms wanna participate in this market and they don't want regulators coming in and reregulating the market.”

“They they see the opportunity in the same way that the startups do. And FINRA is a self regulatory organization.”

“And, you know, putting that $70,000,000 fine on Robinhood was a big enough fine to say, you know what? We don't want the SEC coming in.”

“putting that $70,000,000 fine on Robinhood was a big enough fine to say, you know what? We don't want the SEC coming in.”

“Every single one of them even and another thing people don't realize is every speaker is actually a microphone as well as a speaker.”

“You can actually listen on any house speaker, whether it's a Sonos device or or what have you. And so we've got, you know, our homes are already wired.”

“So the notion of some sort of flatlined or even flatlined at inflation adjusted basic income level for a large number of people will inevitably result in kind of what we're trying to prevent, which is, you know, some sort of decay, societal decay.”

“It's all politics and social behavior. It has nothing to do with science. Like, after nine eleven, there were no more serious, like, terrorist attacks on The United States, but our fucking lives changed dramatically.”

“It has nothing to do with science. Like, after nine eleven, there were no more serious, like, terrorist attacks on The United States, but our fucking lives changed dramatically.”

“We go sit in TSA lines and, you know, get our asses swabbed when we get on an airplane now, And that's still going on twenty years later.”

“California has 33,000,000 acres of forest land. It's about a 100,000,000 acres in total land. Forests make up about a third of our land.”

“Forests make up about a third of our land. So far, we're we're burning three and a half million, so about 10% of our acres.”

“When we burn an acre, we release about 15% of the carbon that's stored in that acre into the atmosphere.”

“I've been fucking shocked by how many people are choosing to pay a premium for vegetarian meat alternatives. I was wrong on this. I I bet against these companies eight years ago.”

“I didn't bet against them, but I chose not to bet for them because I made the argument consumers will only buy stuff that's cheaper and taste as good, and I was wrong.”

“If we could build an algae or a seaweed from scratch or using some basis and use software to resolve what's the right sort of seaweed to create, That will grow like crazy in the oceans.”

“When it gets heavy, sinks to the bottom of the ocean and it literally just pulls carbon out of the atmosphere and drops to these 40,000 foot deep or, you know, 4,000 foot deep kind of wells we have already built around 70% of planet Earth.”

“When it gets heavy, sinks to the bottom of the ocean and it literally just pulls carbon out of the atmosphere and drops to these 40,000 foot deep or, you know, 4,000 foot deep kind of wells we have already built around 70% of planet Earth. We have the tools to do that.”

“And now it is so cost prohibitive. It's something like $10,000,000,000 now from maybe, you know, a 100,000,000, you know, two decades ago.”

“Like if you're six foot away from someone in a room, people are coughing and that room gets filled with those particles over a one hour period.”

“But things of public health, when they get sort of distorted and viewed through a political lens or just idiotic, we view masks as a political statement.”

“Look, we've been arming our police force mistakenly like our military. And we've been doing it for decades now and it makes no sense.”

“I'm a huge fan of ending qualified immunity. I think that doesn't make any sense. I think we have to stop arming our police like their military.”

“And that sources from the fact that we have a second amendment in this country where a lot of people are, you know, you know, gun carriers and are allowed to to have arms.”

“The contra example I would say is if you look at Switzerland where the per capita gun ownership is really high, Canada where per capita gun ownership is really high, what I would tell you is there's a different kind of psychological training that police people go through before they're put on the streets.”

“They should have been trained maybe to just walk into the Wendy's, buy this guy a coffee, and then drive him to the motel that he said that he was staying at.”

“And Facebook is basically a product of Middle America plus kind of like countries outside The United States and, you know, Twitter is about, you know, rich coastal kind of people.”

“we are starting to shift towards valuing comfort over freedom of expression. And that's just kind of the big change that's occurring.”

“So there's gonna, I think there's gonna be a staged release of vaccines that'll probably, believe it or not, start in Q4 of this year.”

“I think there's gonna be a staged release of vaccines that'll probably, believe it or not, start in Q4 of this year. And there's been production ramp up going on in parallel to testing.”

“Yeah. I mean, look. We politicized fucking measles. Thirty percent of people kids now aren't getting vaccinated for measles, which is crazy. Now there's measles outbreaks happening in The US,”

“We politicized fucking measles. Thirty percent of people kids now aren't getting vaccinated for measles, which is crazy. Now there's measles outbreaks happening in The US,”

“I do not think any of us thought that we wanted to apportion our tax dollars to build second shadow army.”

“I I'm a huge fan of ending qualified immunity. I think that doesn't make any sense. I think we have to stop arming our police like their military.”

“I think there's gonna be a staged release of vaccines that'll probably believe it or not, start in q four of this year, and there's been production ramp up going on in parallel to testing.”

“We politicized fucking measles. Thirty percent of people kids now aren't getting vaccinated for measles, which is crazy. And now there's measles outbreaks happening in The US,”

“Trump is incredible at pointing a finger at some third party and saying that's the enemy. I'm the guy who's gonna go defeat him for a year.”

“And two months ago today, I tweeted that the pandemic, that under reaction caused the pandemic and overreaction will cause the depression. And I think that's kind of where we are right now.”

“I tweeted that the pandemic, that under reaction caused the pandemic and overreaction will cause the depression. And I think that's kind of where we are right now.”

“Well, nowhere in the country did the hospitals get overwhelmed and we're still in these lockdowns. And so, you know, I think that it's long overdue for it to end.”

“So, you know, where I come out on this thing is that I think we should end lockdowns but wear masks, and it's very hard to find anybody, you know, in the political spectrum who agrees with that because, you know, one side wants to keep lockdowns going indefinitely and the other doesn't want us to wear masks.”

“where I come out on this thing is that I think we should end lockdowns but wear masks, and it's very hard to find anybody, you know, in the political spectrum who agrees with that because, you know, one side wants to keep lockdowns going indefinitely and the other doesn't want us to wear masks.”

“the data seems to suggest that people 60 who are healthy don't have sort of preexisting conditions are 50 times less likely to develop or there's a 50X greater chance for those 60 in terms of having a really bad outcome. And so for people 60 who don't have these preexisting conditions, it's just not,”

“for people 60 who don't have these preexisting conditions, it's just not, yes, there's always examples to the contrary, but it's not this sort of gigantic risk.”

“And so for two thirds of the population, they don't have a huge risk and we're still locking them down.”

“We've seen in the Asian countries or Czechoslovakia, other places, they've been able to get the so called R naught,”

“One of the things that, you know, I have a strong belief in is like, I think in twenty years we could kind of eradicate all infectious disease.”

“I think in twenty years we could kind of eradicate all infectious disease. The only thing holding that up is regulation because the science is known, the engineering is basically there.”

“There's about a 112,000,000 people in China that work in factories. Factories in China are purpose built. So they're built to make a thing.”

“There's about a 112,000,000 people in China that work in factories. Factories in China are purpose built. So they're built to make a thing. And then they got to get retooled.”

“forty to sixty percent of the population that has never been exposed to SARS coronavirus to the current coronavirus already have activated T cells to the virus.”

“And the reason is that they've had other coronaviruses through a common cold and they've developed this immune response.”

“I was like, Oh, April 7, we'll be back to work. And I also had a bet going with you guys and I said, gonna have less than twenty thousand deaths in The US.”

“I think in twenty years we could kind of eradicate all infectious disease. The only thing holding that up is regulation because the science is known.”

“Factories in China are purpose built. So they're built to make a thing, and then they gotta get retooled if you wanna make another thing.”

“And the reason is that they've had other coronaviruses through a common cold and they've developed this immune response.”

“Steve Mucin, The US Treasury Secretary, was saying that we should expect 20% to 30% of the workforce to be unemployed by this summer if we keep this up.”

“The the world lives on a thirty day food supply. So if you stop food production today, there would only be thirty days of food for the whole world to eat based on our calorie consumption per day, and especially with an isolated border and we import a lot of food in The United States.”

“A paper published showed that in China, up to eighty six percent of people did not realize that they were sick or they were unreported and they had mild symptoms.”

“If doing treatment can reduce fatality rates by up to four x as Korean doctors have claimed, it is worth taking the risk.”

“And this is a time for everyone to activate their CIRT genes and stop focusing on growth and focus on healing.”

“And we're going to start to have measures around washing your hands and masks because you can't stay shut down for that long without literally never being able to open again.”

“But what we really have missed the boat on, and we're still missing the boat on, is knowing who's been infected and to what extent this thing has actually spread already.”

“You should still have the PCR tests, but they're expensive and they take a long time to run and they require chemical labs and all this stuff.”

“So 20 x the impact. They're they they smoke about 50% more, so call it 30 x, and they have a third the number of beds.”

“Remdesivir should be broadly and widely available right now. People shouldn't have to file for compassionate use to get it.”

“48% of all US employees work for a business that's got 10 or fewer employees. Now, these businesses are not only retail.”

“1987, we saw 33% retracement. 2000, we saw 47%. 2008, we saw 56% and we're only 20 into this one.”

“So years later when I was at Google, I came back to this idea about sort of all the world's businesses affected by the weather, maybe there is something they can do about it”

“There is 160,000,000 acres of corn and soybeans planted just in the Midwest Of The United States. Our product costs $40 an acre. There is $6,000,000,000 of revenue we are going after”

“Our product costs $40 an acre. There is $6,000,000,000 of revenue we are going after and our close rate is very, very high.”

“The odds of the guy of being the guy on the left are according to a study and I put the URL up there, point 0006%.”

“And if you were to get a job at Google when you graduate, the anecdotal evidence suggests that your first year salary would be about $105,000 this year.”

“And assuming three founders, your median expected payoff to the founders would be about $300,000 each, which works out to an annualized salary equivalent of $73,000”

“For me, I want to know that I affect the world in an impactful way and in a meaningful way that lasts and that it is going to last once I am gone.”

“So the only way I am going to be able to do that is through entrepreneurism and that's why I call it existential entrepreneurism.”

“Those small variations occur to 40% of farmers. So 40% of our farmers getting some money back at the end of the season”